Looking for an OpenEvidence Alternative in the UK?

OpenEvidence is no longer available to UK doctors. The platform withdrew from the UK and EU on 25 April 2026, citing uncertainty around AI regulation. It went quietly — no replacement announced, no UK handoff.

If you used it, you'll have noticed the gap.

What happened

OpenEvidence was the leading AI clinical Q&A tool in the US — used by over 40% of American physicians. In January 2026 it raised $250m at a $12 billion valuation. By the end of April, it was gone from the UK.

The stated reason was regulatory uncertainty around AI in healthcare. The EU AI Act and the UK's AI regulatory landscape are unsettled enough that several US AI health tools have paused UK expansion or withdrawn entirely. ChatGPT for Clinicians launched the same week and explicitly excluded UK and EEA users.

UK doctors lost two high-profile clinical AI tools in the same fortnight.

What OpenEvidence actually did

OpenEvidence answered clinical questions with referenced, peer-reviewed sources. You typed a question — "what's the evidence on palliative sedation in refractory distress?" — and it returned a synthesised, referenced answer.

It was a point-of-care Q&A tool. Useful when you wanted a referenced answer faster than a PubMed search.

It was not a tool for keeping up with the literature. It didn't surface what was new. It answered what you already knew to ask about.

That distinction matters, because these are two different problems.

For clinical Q&A: what's still available in the UK

iatroX is UK-based, holds MHRA registration and UKCA marking, and is positioning as the UK alternative for AI clinical Q&A. It's the closest direct replacement for OpenEvidence's core use case within the UK regulatory environment.

For keeping up with the literature: that's a different problem

OpenEvidence couldn't tell you about a practice-changing trial published last month unless you already knew to ask about it. Most clinicians don't.

The problem of staying current — knowing what's new, what matters, and what might change how you practice — doesn't get solved by Q&A tools. It gets solved by reading. And most clinicians don't have time to read.

That is the problem we built The Monday Clinical Brief to solve.

What The Monday Clinical Brief offers

Every Monday morning, we send you five of the most important peer-reviewed papers published in your specialty that week. Plain-language summaries. Links to the originals. Nothing else.

We cover 31 specialties. We do the curation. You stay current.

£20 a year. No app. No algorithm. No login required.

Subscribe to The Monday Clinical Brief and never miss a practice-changing paper again.

The bottom line

OpenEvidence was good at answering questions you already had. For that job in the UK, iatroX is worth a look.

But staying current with the literature — knowing what questions to ask in the first place — is a different problem. If that's the one you're trying to solve, that's what we're here for.

Related reading

• ChatGPT for Clinicians launched — and UK doctors are excluded
• Heidi Evidence is excellent — and UK NHS clinicians are excluded