Annals of family medicine
Association of Advanced Access With Primary Care Performance: A Systematic Review
Adadja J, Lafrance S, Gnanvi J et al. · 2026 May 26
Study Type:
Systematic review
Key Question:
Does advanced access appointment scheduling improve primary care performance compared to traditional scheduling systems?
Key Findings:
- All 23 studies showed reduced appointment wait times with advanced access, with 13 demonstrating statistically significant reductions
- Continuity of care improved in 11 of 13 studies (7 statistically significant)
- Patient satisfaction improved in 8 studies (3 statistically significant); all 3 studies examining ED use showed reductions though not statistically significant
Clinical Relevance:
Advanced access scheduling could help UK general practices address ongoing access challenges while maintaining care continuity, particularly relevant given current NHS pressures on appointment availability.
Limitations:
The review included diverse study designs with varying quality, and many outcomes lacked statistical significance despite positive trends.
Annals of family medicine
Death by Rousui in Japan: Rethinking Death, Diagnosis, and Care in an Aging Society
Imanaga T · 2026 May 26
Study Type:
Commentary/perspective piece
Key Question:
How should clinicians approach the diagnosis and care of patients dying from "rousui" (old age) rather than specific disease processes?
Key Findings:
- Rousui (death from old age) is officially recognised in Japan as the third leading cause of death, characterised by gradual decline without specific underlying disease
- Clinical definition remains undefined, creating diagnostic uncertainty and variable approaches to end-of-life care
- This ambiguity can lead to either inappropriate medicalisation or inadequate treatment of dying elderly patients
Clinical Relevance:
With UK's ageing population, this Japanese perspective challenges how we conceptualise and certify natural death from ageing, potentially informing discussions about appropriate end-of-life care pathways in primary care.
Limitations:
Personal commentary rather than empirical research, limiting generalisability of insights.
Annals of family medicine
Multicomponent School of Caring Program to Support Caregivers of Patients With Dementia: A Quasi-Experimental Effectiveness Study in Primary Care
Curto-Romeu C, López GM, Espelta EG et al. · 2026 May 26
Study Type:
Quasi-experimental pre-/post-intervention study with 6-month follow-up
Key Question:
Does a multicomponent School of Caring program delivered in primary care improve outcomes for informal caregivers of people with dementia?
Key Findings:
- 132 caregivers completing the program showed significant improvements in burden, quality of life, self-efficacy, emotional well-being, and social support, sustained at 6 months
- Inexperienced caregivers demonstrated greatest burden reduction compared to experienced caregivers at follow-up
- Daily caregiving time and caregiver health problems were strongest predictors of burden and quality of life outcomes
Clinical Relevance:
Demonstrates that structured group-based caregiver support programs delivered in primary care can meaningfully reduce carer burden and improve wellbeing, with potential applicability to UK general practice serving dementia patients and their families.
Limitations:
Quasi-experimental design without control group limits ability to establish causation and control for confounding factors.
Annals of family medicine
Addressing Primary Care Needs of Cancer Survivors: The Primary Care Engaged Research for Cancer Survivorship Care (PERCS) Initiative
Mollica MA, O'Malley DM, Balasubramanian BA et al. · 2026 May 26
Study Type:
Commentary/initiative description
Key Question:
How can primary care practices be supported to deliver comprehensive survivorship care for cancer survivors through innovative, evidence-based interventions?
Key Findings:
- The PERCS initiative comprises 4 randomized controlled trials testing primary care practice- and health system-level interventions for cancer survivorship care
- Interventions target comprehensive care including management of chronic comorbidities and mitigation of long-term cancer treatment effects
- Studies focus on adult cancer survivors during and/or after active treatment phases
Clinical Relevance:
UK GPs increasingly manage cancer survivors' long-term care needs, and this initiative may inform development of similar evidence-based approaches to improve survivorship care delivery in NHS primary care settings.
Limitations:
This is a protocol/initiative description rather than completed research, so clinical effectiveness data are not yet available.
Annals of family medicine
Prayer for Pain and Anxiety in a Primary Care Setting: A Randomized Controlled Trial
Jacobson K, Zipp J, Jones B et al. · 2026 May 26
Study Type:
Randomized controlled trial
Key Question:
Does in-person intercessory prayer reduce pain and anxiety in primary care patients compared to music control?
Key Findings:
- Prayer group showed significantly larger pain reductions (1-2 points on 0-10 scale) immediately and at 2 weeks versus music control
- Prayer group had larger anxiety reductions (~2 points on GAD-7) immediately and at 2 and 6 weeks
- Effect sizes were larger among Black participants; no adverse events reported
Clinical Relevance:
This suggests prayer may offer a safe, low-cost complementary intervention for pain and anxiety management in UK general practice, particularly relevant for faith-based communities and underserved populations.
Limitations:
Single-site study with predominantly Christian participants limits generalizability to diverse UK populations and healthcare settings.
Annals of family medicine
Breastfeeding Should Not Be a Privilege
Thiyagarajan D · 2026 May 26
Study Type:
Personal narrative/commentary
Key Question:
What barriers prevent equitable access to breastfeeding, and how can clinicians and society address these challenges?
Key Findings:
- An obstetrician-gynaecologist with privileged circumstances experienced significant physical, mental, financial, and time-related barriers to breastfeeding
- Multiple varied costs associated with breastfeeding nearly made it unaffordable even for a well-informed healthcare professional
- Current systems create inequitable access to breastfeeding despite known health benefits
Clinical Relevance:
UK GPs should recognise that breastfeeding barriers extend beyond education to include systemic issues of cost, time, and support—relevant given NHS commitments to reducing health inequalities and supporting infant feeding.
Limitations:
Single personal account limits generalisability of experiences and proposed solutions.
Annals of family medicine
When Routine Care Changes a Life
Bair H · 2026 May 26
Study Type:
Personal narrative/reflective commentary
Key Question:
How can clinicians balance efficient routine care with recognizing the profound impact their work has on patients' lives?
Key Findings:
- A chance encounter with a former optic neuritis patient revealed the disconnect between clinician routine and patient experience—the physician didn't remember the patient, but the patient remembered everything about their "life-altering night"
- The emergency department environment can "muffle" awareness of how routine clinical work represents extraordinary, meaningful moments for patients
- The author explores the tension between maintaining clinical efficiency and honoring the significance of patient encounters
Clinical Relevance:
This reflection is particularly relevant for UK general practice, where time pressures and patient volume can similarly create distance between routine consultations for clinicians and potentially life-changing moments for patients.
Limitations:
As a personal reflection rather than empirical research, findings cannot be generalized beyond individual experience.
Annals of family medicine
Equity Evaluation of an Intervention to Increase Colorectal Cancer Screening at Federally Qualified Health Centers
Ganguly AP, O'Leary MC, Stradtman LR et al. · 2026 May 26
Study Type:
Secondary analysis of a pragmatic randomized controlled trial
Key Question:
Does a multicomponent colorectal cancer screening intervention work equally well across different racial and ethnic groups in federally qualified health centers?
Key Findings:
- The intervention (mailed FIT plus patient navigation) increased screening uptake by 18.3% overall (95% CI 15.6%-20.9%)
- Screening improvements were similar across groups: 16.7% for Hispanic patients, 13.9% for non-Hispanic Black patients, and 20.7% for non-Hispanic White patients (interaction P = 0.79)
- No significant differences in intervention effectiveness between racial/ethnic groups, suggesting equitable benefit
Clinical Relevance:
This intervention could be implemented in UK primary care settings serving diverse populations to improve colorectal cancer screening rates without exacerbating health inequalities between ethnic groups.
Limitations:
Secondary analysis of a trial conducted in US federally qualified health centers may limit generalizability to NHS primary care settings.
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