NICE Clinical Knowledge Summaries (CKS) are updated on a rolling basis, and six primary-care topics were reviewed in July 2026. This round-up gives a one-line takeaway for each, with a link to the source. The authoritative record is the NICE CKS site; this is a summary for awareness, not a substitute for the topic page itself.
This is the latest in our recurring monthly series — the June 2026 edition is here if you missed it. We summarise the changes; we do not replace NICE, and clinical decisions remain the responsibility of the treating clinician.
Two of this month's six change what you might do in a consultation. They are first below.
The updates that matter this month
- Stroke and TIA. Updated in line with the updated NICE guideline on stroke and transient ischaemic attack in over 16s (2025) and the Intercollegiate Stroke Working Party's National clinical guideline for stroke for the United Kingdom and Ireland. Modified-release dipyridamole is no longer recommended as a drug option for antiplatelet therapy, and the recommended indications, doses and duration of use for dual antiplatelet therapy (DAPT) have been amended in line with current evidence. Takeaway: the prescribing change of the month. If you have patients on aspirin plus modified-release dipyridamole, or you initiate DAPT after TIA, read the topic in full before your next review clinic — the detail of dose and duration is the whole point, and this summary is not a safe substitute for it.
- Head injury. Guidance has been added on considering further investigation or referral for people with persistent symptoms consistent with hypopituitarism, aligning with updated NICE guidance. Advice on returning to sport, work and school after injury has been updated to align with the 2022 International Consensus Statement on Concussion in Sport and UK Government guidance. New background sections on common causes and risk factors have also been added. Takeaway: the hypopituitarism prompt is the clinically valuable addition — it is an uncommon consequence of head injury, easily filed under post-concussion syndrome, and now has an explicit trigger to consider it when symptoms are not settling.
- Contraception — assessment. Aligned with the 2025 College of Sexual and Reproductive Health (CoSRH) UK Medical Eligibility Criteria for Contraceptive Use (UKMEC 2025). Takeaway: UKMEC 2025 added conditions and moved some existing ones between risk categories, so a method you would previously have offered without hesitation may now sit differently. Check against the criteria rather than memory — and note UKMEC addresses safety, not efficacy.
- Constipation. Dietary recommendations have been updated and aligned with the British Dietetic Association guidelines for the dietary management of chronic constipation in adults. Information on prescribing in pregnancy and breastfeeding has been updated and moved into the prescribing information section, and the material on factors affecting laxative choice has been folded into the Choice of laxatives section. Takeaway: two practical gains — the dietary advice now has a named guideline behind it, and the pregnancy and breastfeeding prescribing detail sits where you would look for it.
- Palliative care — general issues. The Communication scenario has been deleted, with its content absorbed into the 'Assessment and management approach' and 'The terminal phase' scenarios. Web links to patient and carer information have been added. Takeaway: no change to clinical recommendations, but the topic's structure has moved — if you navigate straight to a bookmarked Communication scenario, it is no longer there. The added carer information is genuinely useful material to hand to families. Our palliative care digest covers the wider evidence picture in this specialty.
- Breastfeeding problems. Reviewed against a May 2026 literature search. No major changes to recommendations. Takeaway: no practice change — the topic has simply been confirmed as current.
How to use this
CKS is a point-of-care reference, not a reading list — but the changes month to month are a useful signal of where guidance is moving. The fastest way to use this round-up is to scan the takeaways, then open the full CKS topic for anything that touches your regular caseload.
Most months bring restructuring and clarification, and the honest summary is "no practice change". July is not one of those months. The stroke and TIA antiplatelet changes affect what you prescribe for a patient group most GPs review regularly, and the head injury addition asks you to consider a diagnosis that is easy to miss.
For the bigger picture on staying current across guidance and the journals, see our pillar guide on how to keep up with the medical literature.
A note on what this post is — and is not
This is a summary for awareness. It is not a substitute for the NICE CKS topic pages, which are the authoritative and current source. Always confirm the recommendation on the CKS topic page before acting on it — that matters more than usual for the stroke and TIA changes above. Clinical decisions remain the responsibility of the treating clinician.
Reading a round-up like this one counts towards CPD once you have reflected on it — see does reading count as CPD? for what a credit-bearing entry needs, and how many CPD points UK doctors need for the wider picture.
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Frequently Asked Questions
What is NICE CKS?
NICE Clinical Knowledge Summaries (CKS) are concise, regularly updated summaries of the evidence base and best-practice guidance for over 370 primary-care topics, free to access in the UK. They are one of the most-used point-of-care references in UK general practice.
Which CKS topics were updated in July 2026?
Six topics were reviewed in July 2026: stroke and TIA (modified-release dipyridamole is no longer recommended as an antiplatelet option, and the indications, doses and duration of dual antiplatelet therapy have been amended), head injury (investigation or referral for persistent symptoms consistent with hypopituitarism, plus return to sport, work and school), contraception assessment (aligned with UKMEC 2025), constipation (dietary advice aligned with British Dietetic Association guidelines, and prescribing in pregnancy and breastfeeding), palliative care general issues (the Communication scenario has been absorbed into two other scenarios), and breastfeeding problems (reviewed, no major changes).
What changed in the CKS stroke and TIA topic?
The topic has been updated in line with the updated NICE guideline on stroke and transient ischaemic attack in over 16s (2025) and the Intercollegiate Stroke Working Party's National clinical guideline for stroke for the United Kingdom and Ireland. Modified-release dipyridamole is no longer recommended as a drug option for antiplatelet therapy, and the recommended indications, doses and duration of use for dual antiplatelet therapy have been amended in line with current evidence. Confirm the current recommendation on the CKS topic page before changing any individual patient's antiplatelet regimen.
Why does the head injury update mention hypopituitarism?
The July 2026 review added guidance on considering further investigation or referral for people with persistent symptoms consistent with hypopituitarism after head injury, aligning CKS with updated NICE guidance. Post-traumatic hypopituitarism is an uncommon but recognised consequence of head injury and is easily attributed to post-concussion syndrome, so the addition gives a prompt to consider it in someone whose symptoms are not settling.
Where can I see the full list of recent CKS changes?
The authoritative source is the NICE CKS website, which lists new and updated topics with dates. This post is a summary for awareness — always confirm the current recommendation against the CKS topic page before acting on it.
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